A recent study published by doctors at Newcastle University found that dietary supplements with resistant starch do not reduce the risk of colorectal cancer in those with Lynch syndrome. The study was part of the CAPP2 or Colorectal Adenoma/carcinoma Prevention Programme. The point of the study was to compare the effects of dietary supplements with that of diets high in dietary fiber. Specifically the study looked at those suffering from lynch syndrome, a genetic predisposition to colorectal cancer.
The study, led by John Mathers and company, divided 918 patients into either placebo groups or a daily regimen of 30 g of resistant starch as a dietary supplement. The study looked at another study’s results that treated patients for 29 months, which found that resistant starch had no effect. This study looked at patients for over 10 years but found after 2 years taking the resistant starch the results were the same as taking the placebo. Interestingly, the study found that those who took resistant starch for less than two years actually had a 2.38 increase in incidents of colon cancer. The authors of the study are not sure if this is a fluke or actually a short-term adverse effect. Prior to the study, resistant starch, like other carbohydrates, were believed to be beneficial for the colon when in combination with other carbohydrates.